Gene Symbol | CEP135 |
---|---|
Entrez Gene | 9662 |
Alt Symbol | CEP4, KIAA0635, MCPH8 |
Species | Human |
Gene Type | protein-coding |
Description | centrosomal protein 135kDa |
Other Description | centrosomal protein 4|centrosomal protein of 135 kDa|centrosome protein cep135 |
Swissprots | Q58F25 B2RMY0 Q66GS9 Q9H8H7 O75130 |
Accessions | Q66GS9 AB014535 BAA31610 AK023683 AK309554 BC012003 AAH12003 BC136535 AAI36536 BC136536 AAI36537 BF448516 BK005586 DAA05590 BU734129 CA438857 DA944890 XM_005265788 XP_005265845 XM_006714055 XP_006714118 XM_011534412 XP_011532714 NM_025009 NP_079285 NM_014645 |
Function | Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. {ECO:0000269|PubMed:17681131, ECO:0000269|PubMed:18851962}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:17681131}. Note=During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles. |
CEP135 CRISPR/Cas9 KO Plasmid (h) - sc-411306 from Santa Cruz Biotechnology
|
||||||||
CEP135 HDR Plasmid (h) - sc-411306-HDR from Santa Cruz Biotechnology
|
||||||||
CEP135 Double Nickase Plasmid (h) - sc-411306-NIC from Santa Cruz Biotechnology
|
||||||||
CEP135 Double Nickase Plasmid (h2) - sc-411306-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CEP135 CRISPR Activation Plasmid (h) - sc-411306-ACT from Santa Cruz Biotechnology
|
||||||||
CEP135 CRISPR Activation Plasmid (h2) - sc-411306-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CEP135 Lentiviral Activation Particles (h) - sc-411306-LAC from Santa Cruz Biotechnology
|
||||||||
CEP135 Lentiviral Activation Particles (h2) - sc-411306-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CEP135 siRNA (h) - sc-88951 from Santa Cruz Biotechnology
|
||||||||
CEP135 shRNA Plasmid (h) - sc-88951-SH from Santa Cruz Biotechnology
|
||||||||
CEP135 shRNA (h) Lentiviral Particles - sc-88951-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU054481 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN5959 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5959 from Sigma-Aldrich
|
||||||||
CEP135 siRNA (Human) - CRH6437 from Cohesion Biosciences
|
||||||||
CEP135 - MBS8205220 from MyBioSource
|
||||||||
shRNA set against Human CEP135 (NM_025009.4) - SHH261813 from Creative biogene
|
||||||||
Human CEP135 siRNA - orb266939 from Biorbyt
|
||||||||
CEP135 shRNA Plasmid (Human) - CHH6437 from Cohesion Biosciences
|
||||||||
CEP135 miRNA 3'UTR clone - MiUTR4H-TG02017 from Creative biogene
|