| Gene Symbol |
CEP135
|
| Entrez Gene |
9662
|
| Alt Symbol |
CEP4, KIAA0635, MCPH8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
centrosomal protein 135kDa
|
| Other Description |
centrosomal protein 4|centrosomal protein of 135 kDa|centrosome protein cep135
|
| Swissprots |
Q58F25 B2RMY0 Q66GS9 Q9H8H7 O75130
|
| Accessions |
Q66GS9 AB014535 BAA31610 AK023683 AK309554 BC012003 AAH12003 BC136535 AAI36536 BC136536 AAI36537 BF448516 BK005586 DAA05590 BU734129 CA438857 DA944890 XM_005265788 XP_005265845 XM_006714055 XP_006714118 XM_011534412 XP_011532714 NM_025009 NP_079285 NM_014645
|
| Function |
Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. {ECO:0000269|PubMed:17681131, ECO:0000269|PubMed:18851962}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:17681131}. Note=During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles.
|