| Gene Symbol | WNT2 |
|---|---|
| Entrez Gene | 7472 |
| Alt Symbol | INT1L1, IRP |
| Species | Human |
| Gene Type | protein-coding |
| Description | wingless-type MMTV integration site family member 2 |
| Other Description | Int-1-related protein|int-1-like protein 1|protein Wnt-2|secreted growth factor |
| Swissprots | A4D0V1 Q75N05 Q9UDP9 P09544 |
| Accessions | AAB67043 AAD28351 CAI38640 CCQ43213 EAL24355 EAW83525 P09544 AK056742 BAG51800 BC029854 AAH29854 BC078170 AAH78170 BT019608 AAV38415 DQ892457 ABM83383 DQ895669 ABM86595 X07876 CAA30725 NM_003391 NP_003382 NR_024047 |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Expressed in brain in the thalamus, in fetal and adult lung and in placenta. {ECO:0000269|PubMed:11449391}. |
| Top Pathways | Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection |