| Gene Symbol |
IL4
|
| Entrez Gene |
751514
|
| Alt Symbol |
-
|
| Species |
Cat
|
| Gene Type |
protein-coding
|
| Description |
interleukin 4
|
| Other Description |
B-cell stimulatory factor 1|BSF-1|IL-4|interleukin-4|lymphocyte stimulatory factor 1
|
| Swissprots |
P79170 P55030 O62774
|
| Accessions |
CAA60856 P55030 AF054602 AAC15975 U39634 AAB42052 NM_001043339 NP_001036804
|
| Function |
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, PI3K-Akt signaling pathway, Measles, Leishmaniasis, Intestinal immune network for IgA production
|
