ADAMTS1

Gene Symbol ADAMTS1
Entrez Gene 9510
Alt Symbol C3-C5, METH1
Species Human
Gene Type protein-coding
Description ADAM metallopeptidase with thrombospondin type 1 motif, 1
Other Description A disintegrin and metalloproteinase with thrombospondin motifs 1|ADAM-TS 1|ADAM-TS1|ADAMTS-1|METH-1|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1|human metalloproteinase with thrombospondin type 1 motifs
Swissprots Q9UHI8 D3DSD5 Q9P2K0 Q9UH83 Q9UP80 Q9NSJ8
Accessions BAA95502 EAX09951 EAX09952 Q9UHI8 AB037767 BAA92584 AF060152 AAD48080 AF170084 AAF15317 AF207664 AAF23772 AK023795 AK129873 BAC85245 AK314475 BAG37080 AL162080 CAB82413 AW163724 BC036515 AAH36515 BX647388 CAI46043 DQ108407 AAZ73034 DQ896765 ABM87764 EU176454 ABW03905 NM_006988 NP_008919
Function Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture. {ECO:0000250, ECO:0000269|PubMed:10438512}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250}.

ADAMTS1 (D5G4Z) Rabbit mAb - 12897 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5G4Z
Western blot analysis of extracts from various cell lines using ADAMTS1 (D5G4Z) Rabbit mAb.

ADAMTS-1 (3C8F4) - sc-47727 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ADAMTS-1 (3C8F4): sc-47727. Western blot analysis of unreduced 87 kDa human recombinant ADAMTS-1 purified from transfected 293T cells.

ADAMTS-1 (3E4C6B4) - sc-47726 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ADAMTS-1 (3E4C6B4): sc-47726. Western blot analysis of 65 kDa (A) and 87 kDa (B) unreduced recombinant ADAMTS-1 purified from transfected 293T cells.

ADAMTS-1 (A-17) - sc-5466 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ADAMTS-1 (A-19) - sc-5467 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ADAMTS-1 (A-19): sc-5467. Western blot analysis of ADAMTS-1 expression in SW480 (A) and CSMLO (B) whole cell lysates.

ADAMTS-1 (C-13) - sc-5463 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ADAMTS-1 (H-60) - sc-25581 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ADAMTS-1 (H-60): sc-25581. Western blot analysis of mature ADAMTS-1 expression in KNRK whole cell lysate.

ADAMTS-1 (L-16) - sc-31080 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ADAMTS-1 (30D445.1) - sc-52911 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl ascites
Host Mouse
Clonality Monoclonal
ADAMTS-1 (30D445.1): sc-52911. Western blot analysis of ADAMTS-1 expression in ES-2 (A), OV-90 (B), Caki-1 (C) and A-375 (D) whole cell lysates.

Anti-ADAMTS1 antibody - ab126255 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab126255 stained PC3 cells. The cells were 4% formaldehyde fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab126255 at 1µg/ml overnight at +4°C. The secondary antibody (pseudo-colored green) was Dylight® 488 goat anti- rabbit (ab96899) IgG (H+L) preadsorbed, used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

Anti-ADAMTS1 antibody - ab113847 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ADAMTS1 antibody (ab113847) at 1 µg/mlLane 1 : U2OS (Human osteosarcoma cell line) Whole Cell LysateLane 2 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-ADAMTS1 antibody - ab84793 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab84793 at a 1/100 dilution staining ADAMTS1 in Human kidney tissue.

Anti-ADAMTS1 antibody - ab116588 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry Image of Human Testis, Vessels (formalin-fixed, paraffin-embedded) stained with ADAMTS1 antibody (ab116588) at 20 &microg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-ADAMTS1 antibody - Aminoterminal end - ab28284 from Abcam

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ADAMTS1 antibody - Aminoterminal end (ab28284) at 1/2500 dilution + SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Anti-ADAMTS1 antibody - Carboxyterminal end - ab39194 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab39194 stained Hek293 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab39194, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-ADAMTS1 antibody - Propeptide domain - ab39195 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ADAMTS1 Antibody (aa295-306) - LS-C11801 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ADAMTS1 Antibody (C-Terminus) - LS-C47072 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ADAMTS1 Antibody (aa295-306) - LS-C124987 from LifeSpan Bioscience

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-ADAMTS1 Antibody (aa50-252) - LS-C124988 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ADAMTS1 Antibody - LS-C136822 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADAMTS1 Antibody - LS-C137037 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADAMTS1 Antibody (aa476-614) - LS-C292566 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant ADAMTS1.

Anti-ADAMTS1 Antibody (clone 1B8) - LS-C139204 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B8
Detection limit for recombinant GST tagged ADAMTS1 is approximately 1 ng/ml as a capture antibody.

Anti-ADAMTS1 Antibody (aa476-614) - LS-C292361 from LifeSpan Bioscience

Prices $405.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Western blot of recombinant ADAMTS1.
Search more