CLPS

Gene Symbol CLPS
Entrez Gene 1208
Alt Symbol -
Species Human
Gene Type protein-coding
Description colipase, pancreatic
Other Description colipase|pancreatic colipase preproprotein
Swissprots Q5U809 Q5T9G7 P04118
Accessions AAB05818 EAX03850 EAX03851 P04118 AY780648 AAV35728 AY780649 AAV35729 BC007061 AAH07061 BC017897 AAH17897 BC025693 BC043489 BI439786 BP321569 BP322637 BP324927 BQ271978 BT006812 AAP35458 J02883 AAA52054 JF432763 ADZ15980 NM_001252597 NP_001239526 NM_001252598 NP_001239527 NM_001832 NP_001823
Function Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
Subcellular Location Secreted.
Tissue Specificity Expressed by the pancreas.
Top Pathways Fat digestion and absorption