Gene Symbol |
CLPS
|
Entrez Gene |
1208
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
colipase, pancreatic
|
Other Description |
colipase|pancreatic colipase preproprotein
|
Swissprots |
Q5U809 Q5T9G7 P04118
|
Accessions |
AAB05818 EAX03850 EAX03851 P04118 AY780648 AAV35728 AY780649 AAV35729 BC007061 AAH07061 BC017897 AAH17897 BC025693 BC043489 BI439786 BP321569 BP322637 BP324927 BQ271978 BT006812 AAP35458 J02883 AAA52054 JF432763 ADZ15980 NM_001252597 NP_001239526 NM_001252598 NP_001239527 NM_001832 NP_001823
|
Function |
Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Expressed by the pancreas.
|
Top Pathways |
Fat digestion and absorption
|