Gene Symbol | VDR |
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Entrez Gene | 7421 |
Alt Symbol | NR1I1, PPP1R163 |
Species | Human |
Gene Type | protein-coding |
Description | vitamin D (1,25- dihydroxyvitamin D3) receptor |
Other Description | 1,25-dihydroxyvitamin D3 receptor|nuclear receptor subfamily 1 group I member 1|protein phosphatase 1, regulatory subunit 163|vitamin D nuclear receptor variant 1|vitamin D3 receptor |
Swissprots | G3V1V9 P11473 B2R5Q1 Q5PSV3 |
Accessions | AAP88938 AAR10771 AAR19315 AAR19316 AAV85448 AGU41796 AGU41797 AGU41798 AGU41799 AGU41800 AGU41801 AGU41802 AGU41803 AGU41804 AGU41805 AGU41806 AGU41807 AGU41808 AGU41809 AGU41810 AGU41811 AID81985 BAA83389 CAC42552 EAW57959 EAW57960 EAW57961 EAW57962 EAW57963 P11473 AB307700 BAH02291 AF026260 AAB95155 AK024830 AK225844 AK299446 BAG61419 AK312267 BAG35198 BC033465 BC060832 AAH60832 BM685276 BM908433 BQ002808 BX355584 CF138099 DA721726 EU446665 ABZ92194 EU831779 ACE87297 EU831857 ACE86616 HQ692836 ADZ17347 J03258 AAA61273 M65208 AAA61274 X67482 CAA47824 XM_006719587 XP_006719650 XM_011538720 XP_011537022 NM_000376 NP_000367 NM_001017535 NP_001017535 NM_001017536 NP_001017536 |
Function | Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. {ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:15728261, ECO:0000269|PubMed:16252006, ECO:0000269|PubMed:16913708}. |
Subcellular Location | Nucleus. |
Top Pathways | Mineral absorption, Endocrine and other factor-regulated calcium reabsorption, Tuberculosis |
VDR-Over-expression-Lysate - LY10178a from Abgent, a WuXi AppTec company
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VDR 293T Cell Transient Overexpression Lysate(Denatured) - H00007421-T01 from Acris Antibodies
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VDR 293 Cell Lysate - 410249 from ABBIOTEC
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VDR 293 Cell Lysate - 409783 from ABBIOTEC
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VDR/NR1I1/Vitamin D Receptor Overexpression Lysate (Native) - NBL1-17711 from Novus Biologicals
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VDR (h): 293T Lysate - sc-178118 from Santa Cruz Biotechnology
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VDR (h2): 293T Lysate - sc-178119 from Santa Cruz Biotechnology
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VDR Over-expression Lysate Product - GWB-BBCFAC from Genway Biotech
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VDR Over-expression Lysate Product - GWB-800895 from Genway Biotech
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Human VDR / NR1I1 Insect Cell Lysate (WB positive control) - 12025-H08BL-300 from Sino Biological
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VDR/NR1I1/Vitamin D Receptor Overexpression Lysate (Native) - NBP2-11022 from Novus Biologicals
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VDR/NR1I1/Vitamin D Receptor Overexpression Lysate (Native) - NBP2-11216 from Novus Biologicals
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VDR/NR1I1/Vitamin D Receptor Overexpression Lysate (Denatured) - H00007421-T01 from Novus Biologicals
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Human VDR Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175150 from Biorbyt
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Panoply™ Human VDR Knockdown Stable Cell Line - CSC-DC017262 from Creative biogene
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VDR Knockout Cell Line-HeLa - CSC-RT1819 from Creative biogene
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VDR KO Cell Lysate-HeLa - CLKO-1668 from Creative biogene
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