Gene Symbol |
CD2
|
Entrez Gene |
914
|
Alt Symbol |
LFA-2, SRBC, T11
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
CD2 molecule
|
Other Description |
CD2 antigen (p50), sheep red blood cell receptor|LFA-3 receptor|T-cell surface antigen CD2|T-cell surface antigen T11/Leu-5|erythrocyte receptor|lymphocyte-function antigen-2|rosette receptor
|
Swissprots |
Q96TE5 P06729
|
Accessions |
AAA53095 CAA30721 CAJ86523 CBX51829 EAW56661 P06729 AK127925 AK223393 BAD97113 AK301154 BAG62744 AK303367 BAG64425 AK310676 AK313614 BAG36377 BC033583 AAH33583 DQ890953 ABM81879 DQ894115 ABM85041 M14362 AAA35571 M16336 AAA51946 M16445 AAA51738 XM_005271320 XP_005271377 NM_001767 NP_001758
|
Function |
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.
|
Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
Top Pathways |
Hematopoietic cell lineage, Cell adhesion molecules (CAMs)
|