GSTA1

Gene Symbol GSTA1
Entrez Gene 2938
Alt Symbol GST2, GSTA1-1, GTH1
Species Human
Gene Type protein-coding
Description glutathione S-transferase alpha 1
Other Description GST HA subunit 1|GST class-alpha member 1|GST, class alpha, 1|GST-epsilon|S-(hydroxyalkyl)glutathione lyase A1|glutathione S-alkyltransferase A1|glutathione S-aryltransferase A1|glutathione S-transferase 2|glutathione S-transferase A1|glutathione S-transferase Ha subunit 1
Swissprots Q5GHF8 Q14750 P08263 Q5SZC1
Accessions AAA35938 AAB20973 EAX04385 P08263 AK293371 BAH11495 AK310324 AL096729 AY532928 AAT06769 BC053578 AAH53578 BC110891 AAI10892 BG430521 BI762344 BM973137 CA841071 CR407656 CAG28584 DC339498 HQ448093 ADQ32574 M14777 AAA52618 M15872 AAA70226 M21758 AAA52615 M25627 AAA36174 S49975 AAB24012 XM_005249034 XP_005249091 NM_145740 NP_665683
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. {ECO:0000269|PubMed:20606271}.
Subcellular Location Cytoplasm.
Tissue Specificity Liver.
Top Pathways Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450