| Gene Symbol | Pla2g1b |
|---|---|
| Entrez Gene | 18778 |
| Alt Symbol | Pla2a, sPLA2IB |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | phospholipase A2, group IB, pancreas |
| Other Description | PLA2-Ib|group IB phospholipase A2|phosphatidylcholine 2-acylhydrolase 1B|phospholipase A2 |
| Swissprots | Q9D7E2 Q9D884 A6H6K5 Q9Z0Y2 |
| Accessions | AAF02298 EDL19858 Q9Z0Y2 AF094610 AAG27064 AF097637 AAD19896 AF162712 AAD45806 AF187852 AAF44297 AK007730 BAB25218 AK007797 BAB25263 AK008331 BAB25608 AK008664 BAB25819 AK008668 BAB25822 AK008841 BAB25922 AK008934 BAB25976 AK008936 BAB25978 AK009314 BAB26212 AK019009 AK028104 BAC25749 AK028134 BAC25763 BC145546 BC145908 AAI45909 BC145910 AAI45911 XM_006530199 XP_006530262 NM_011107 NP_035237 |
| Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. |
| Subcellular Location | Secreted. Note=secreted from pancreatic acinar cells in its inactive form. {ECO:0000250}. |
| Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |