Gene Symbol | EVA1A |
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Entrez Gene | 84141 |
Alt Symbol | FAM176A, TMEM166 |
Species | Human |
Gene Type | protein-coding |
Description | eva-1 homolog A (C. elegans) |
Other Description | family with sequence similarity 176, member A|protein FAM176A|protein eva-1 homolog A|transmembrane protein 166 |
Swissprots | Q9HC41 Q9H8M9 D6W5J3 |
Accessions | AAY14774 CAE91766 EAW99591 EAW99592 EAW99593 EAW99594 Q9H8M9 AF177337 AAG17981 AK023453 BAB14580 AW016395 BC016157 AAH16157 BC063016 AAH63016 BE892427 BP276065 CR457314 CAG33595 NM_001135032 NP_001128504 NM_032181 NP_115557 |
Function | Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis. {ECO:0000269|PubMed:17492404, ECO:0000269|PubMed:19029833}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:17492404}; Single-pass membrane protein {ECO:0000269|PubMed:17492404}. Lysosome membrane {ECO:0000269|PubMed:17492404}; Single-pass membrane protein {ECO:0000269|PubMed:17492404}. |
Tissue Specificity | Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle. {ECO:0000269|PubMed:17492404}. |
TMEM166 CRISPR/Cas9 KO Plasmid (h) - sc-413564 from Santa Cruz Biotechnology
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TMEM166 HDR Plasmid (h) - sc-413564-HDR from Santa Cruz Biotechnology
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TMEM166 Double Nickase Plasmid (h) - sc-413564-NIC from Santa Cruz Biotechnology
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TMEM166 Double Nickase Plasmid (h2) - sc-413564-NIC-2 from Santa Cruz Biotechnology
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TMEM166 CRISPR Activation Plasmid (h) - sc-413564-ACT from Santa Cruz Biotechnology
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TMEM166 CRISPR Activation Plasmid (h2) - sc-413564-ACT-2 from Santa Cruz Biotechnology
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TMEM166 Lentiviral Activation Particles (h) - sc-413564-LAC from Santa Cruz Biotechnology
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TMEM166 Lentiviral Activation Particles (h2) - sc-413564-LAC-2 from Santa Cruz Biotechnology
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EVA1A siRNA (h) - sc-94711 from Santa Cruz Biotechnology
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EVA1A shRNA Plasmid (h) - sc-94711-SH from Santa Cruz Biotechnology
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EVA1A shRNA (h) Lentiviral Particles - sc-94711-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU027231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8241 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06906 from Sigma-Aldrich
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EVA1A siRNA (Human) - CRJ3319 from Cohesion Biosciences
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EVA1A - MBS8203255 from MyBioSource
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shRNA set against Human FAM176A (NM_032181.2) - SHH290245 from Creative biogene
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Human EVA1A siRNA - orb273820 from Biorbyt
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EVA1A shRNA Plasmid (Human) - CHJ3319 from Cohesion Biosciences
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FAM176A miRNA 3'UTR clone - MiUTR3H-14845 from Creative biogene
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FAM176A miRNA 3'UTR clone - MiUTR3H-14846 from Creative biogene
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