| Gene Symbol | CCD8 |
|---|---|
| Entrez Gene | 829417 |
| Alt Symbol | ATCCD8, MAX4, MORE AXILLARY BRANCHING 4, T16I18.20, T16I18_20, carotenoid cleavage dioxygenase 8 |
| Species | Arabidopsis thaliana |
| Gene Type | protein-coding |
| Description | carotenoid cleavage dioxygenase 8 |
| Other Description | - |
| Swissprots | Q8VY26 Q9M079 |
| Accessions | AEE86121 CAD10241 Q8VY26 AY074264 AAL66961 AY133732 AAM91666 NM_119434 NP_195007 |
| Function | Involved in strigolactones biosynthesis by cleaving the C(27) 9-cis-10'-apo-beta-carotenal produced by CCD7. Produces the C(19) carlactone and a C(8) hydroxyaldehyde. Also shows lower activity with all-trans-10'-apo-beta-carotenal producing a C(9) dialdehyde and the C(18) 13-apo-beta-carotenone. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds. Also active on other carotenoid substrates like licopene or zeaxanthin. {ECO:0000269|PubMed:12815068, ECO:0000269|PubMed:15342640, ECO:0000269|PubMed:16507088}. |
| Subcellular Location | Plastid, chloroplast {ECO:0000269|PubMed:16507088}. |
| Tissue Specificity | Expressed in flowers, siliques, inflorescence stems, petiole and leaves, and at a much higher level in roots. {ECO:0000269|PubMed:12815068, ECO:0000269|PubMed:16507088, ECO:0000269|PubMed:21243360}. |
| Top Pathways | Carotenoid biosynthesis |