| Gene Symbol | SEC63 |
|---|---|
| Entrez Gene | 11231 |
| Alt Symbol | DNAJC23, ERdj2, PRO2507, SEC63L |
| Species | Human |
| Gene Type | protein-coding |
| Description | SEC63 homolog (S. cerevisiae) |
| Other Description | translocation protein SEC63 homolog |
| Swissprots | O95380 Q9UGP8 Q5THN4 Q8IWL0 Q9NTE0 Q86VS9 |
| Accessions | EAW48392 Q9UGP8 AF100141 AAC83375 AF119883 AAF69637 AI559292 AJ011779 CAB46275 AJ420532 AK001465 AK027374 BAG51309 AK074835 BAG52012 AL137338 CAB70701 BC001153 BC009066 BC023598 AAH23598 BC047221 AAH47221 BC048287 AAH48287 BE972247 BM764168 DB049187 X75689 XM_011535399 XP_011533701 NM_007214 NP_009145 NM_018529 |
| Function | Required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane. |
| Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Tissue Specificity | Widely expressed, with high levels in the liver. {ECO:0000269|PubMed:15133510}. |
| Top Pathways | Protein export, Protein processing in endoplasmic reticulum |