| Gene Symbol | CTSB |
|---|---|
| Entrez Gene | 1508 |
| Alt Symbol | APPS, CPSB |
| Species | Human |
| Gene Type | protein-coding |
| Description | cathepsin B |
| Other Description | APP secretase|amyloid precursor protein secretase|cathepsin B1|cysteine protease |
| Swissprots | B3KRR5 B3KQR5 Q503A6 Q96D87 P07858 |
| Accessions | AAL99368 AAL99369 EAW65630 EAW65631 EAW65632 EAW65633 EAW65634 EAW65635 EAW65636 P07858 AK075393 BAG52127 AK092070 BAG52477 AK097384 BAG53460 AK098296 AK128472 AK130184 AK290239 BAF82928 AK296845 BAG59411 AK297687 BAG60046 AL543654 BC010240 AAH10240 BC095408 AAH95408 BG770805 BM008741 BX647765 CAI46053 BX647952 BX648239 CB997355 L16510 AAC37547 L38712 M13230 AAA52125 M14221 AAA52129 Y18460 CAA77178 XM_006716244 XP_006716307 XM_006716245 XP_006716308 XM_011543812 XP_011542114 NM_001908 NP_001899 NM_147780 NP_680090 NM_147781 NP_680091 NM_147782 NP_680092 NM_147783 NP_680093 |
| Function | Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. |
| Subcellular Location | Lysosome. Melanosome. Secreted, extracellular space {ECO:0000250}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Top Pathways | Lysosome, Antigen processing and presentation |