| Gene Symbol | PLA2G2D |
|---|---|
| Entrez Gene | 26279 |
| Alt Symbol | PLA2IID, SPLASH, sPLA2-IID, sPLA2S |
| Species | Human |
| Gene Type | protein-coding |
| Description | phospholipase A2, group IID |
| Other Description | GIID sPLA2|group IID secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2D|secretory phospholipase A2s|secretory-type PLA, stroma-associated homolog |
| Swissprots | Q9UNK4 Q9UK01 B1AEL9 A8K2Z1 |
| Accessions | ACA06110 EAW94915 Q9UNK4 AF112982 AAD51390 AF188625 AAF09020 AK026347 AK290406 BAF83095 AK301396 BAG62931 AK310156 AK311903 BAG34844 AM392918 CAL37796 AM392954 CAL37832 AM392977 CAL37855 AM393597 CAL38474 AM393824 CAL38699 BC025706 AAH25706 DC295429 NM_001271814 NP_001258743 NM_012400 NP_036532 |
| Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. L-alpha-1-palmitoyl-2- linoleoyl phosphatidylethanolamine is more efficiently hydrolyzed than the other phospholipids examined. |
| Subcellular Location | Secreted {ECO:0000305}. |
| Tissue Specificity | Broadly expressed. |
| Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |