| Gene Symbol | CXCL1 |
|---|---|
| Entrez Gene | 2919 |
| Alt Symbol | FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| Other Description | C-X-C motif chemokine 1|GRO-alpha(1-73)|GRO1 oncogene (melanoma growth stimulating activity, alpha)|GRO1 oncogene (melanoma growth-stimulating activity)|MGSA alpha|fibroblast secretory protein|growth-regulated alpha protein|melanoma growth stimulatory activity alpha|neutrophil-activating protein 3 |
| Swissprots | P09341 Q9UCR7 |
| Accessions | AAA03452 AAP13103 CAA38361 CBX54348 CCD62019 EAX05693 P09341 BC011976 AAH11976 BG121608 BM554448 BM996663 BQ000742 BT006880 AAP35526 CB112830 DQ893591 ABM84517 DQ894941 ABM85867 J03561 AAA35933 X12510 CAA31027 NM_001511 NP_001502 NR_046035 |
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. {ECO:0000269|PubMed:10095777}. |
| Subcellular Location | Secreted. |
| Top Pathways | TNF signaling pathway, Cytokine-cytokine receptor interaction, Legionellosis, Salmonella infection, Rheumatoid arthritis |