RBSN

Gene Symbol RBSN
Entrez Gene 64145
Alt Symbol Rabenosyn-5, ZFYVE20
Species Human
Gene Type protein-coding
Description rabenosyn, RAB effector
Other Description 110 kDa protein|FYVE finger-containing Rab5 effector protein rabenosyn-5|RAB effector RBSN|rabenosyn-5|zinc finger, FYVE domain containing 20
Swissprots Q59EY8 C9J4P5 Q8NAQ1 Q9H1K0 Q3KP30 B4DWY8
Accessions EAW64220 EAW64221 Q9H1K0 AB209673 BAD92910 AK054598 AK092312 BAC03860 AK291288 BAF83977 AK301735 BAG63200 AL833545 AY009133 AAG33246 BC032628 BC106940 AAI06941 BF513881 BX111409 BX640925 CAE45963 DA320360 XM_005265384 XP_005265441 XM_005265385 XP_005265442 XM_005265386 XP_005265443 XM_005265387 XP_005265444 XM_011534001 XP_011532303 XM_011534002 XP_011532304 NM_001302378 NP_001289307 NM_022340 NP_071735 NR_126155
Function Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:11062261, PubMed:11788822, PubMed:15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:22308388). {ECO:0000269|PubMed:11062261, ECO:0000269|PubMed:11788822, ECO:0000269|PubMed:15020713, ECO:0000269|PubMed:22308388}.
Subcellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane {ECO:0000269|PubMed:22308388}; Lipid-anchor. Note=Enriched in endosomes that are in close proximity to clathrin-enriched regions at the cell surface. {ECO:0000269|PubMed:22308388}.
Top Pathways Endocytosis

Rabenosyn-5 CRISPR/Cas9 KO Plasmid (h) - sc-410091 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rabenosyn-5 HDR Plasmid (h) - sc-410091-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rabenosyn-5 Double Nickase Plasmid (h) - sc-410091-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rabenosyn-5 Double Nickase Plasmid (h2) - sc-410091-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rabenosyn-5 CRISPR Activation Plasmid (h) - sc-410091-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rabenosyn-5 CRISPR Activation Plasmid (h2) - sc-410091-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rabenosyn-5 Lentiviral Activation Particles (h) - sc-410091-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rabenosyn-5 Lentiviral Activation Particles (h2) - sc-410091-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Rabenosyn-5 siRNA (h) - sc-76333 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Rabenosyn-5 shRNA Plasmid (h) - sc-76333-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Rabenosyn-5 shRNA (h) Lentiviral Particles - sc-76333-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU000891 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23205 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23205 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ZFYVE20 siRNA (Human) - CRJ1943 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Rabenosyn 5 RNAi - H00064145-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ZFYVE20 - MBS8222871 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZFYVE20 (NM_022340.2) - SHH452480 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ZFYVE20(NM_022340.2) - SHL152400 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZFYVE20 siRNA - orb272444 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFYVE20 shRNA Plasmid (Human) - CHJ1943 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZFYVE20 miRNA 3'UTR clone - MiUTR1H-11445 from Creative biogene

Species Reactivities Human
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