RBSN

Gene Symbol RBSN
Entrez Gene 64145
Alt Symbol Rabenosyn-5, ZFYVE20
Species Human
Gene Type protein-coding
Description rabenosyn, RAB effector
Other Description 110 kDa protein|FYVE finger-containing Rab5 effector protein rabenosyn-5|RAB effector RBSN|rabenosyn-5|zinc finger, FYVE domain containing 20
Swissprots Q59EY8 C9J4P5 Q8NAQ1 Q9H1K0 Q3KP30 B4DWY8
Accessions EAW64220 EAW64221 Q9H1K0 AB209673 BAD92910 AK054598 AK092312 BAC03860 AK291288 BAF83977 AK301735 BAG63200 AL833545 AY009133 AAG33246 BC032628 BC106940 AAI06941 BF513881 BX111409 BX640925 CAE45963 DA320360 XM_005265384 XP_005265441 XM_005265385 XP_005265442 XM_005265386 XP_005265443 XM_005265387 XP_005265444 XM_011534001 XP_011532303 XM_011534002 XP_011532304 NM_001302378 NP_001289307 NM_022340 NP_071735 NR_126155
Function Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3) (PubMed:11062261, PubMed:11788822, PubMed:15020713). Plays a role in the recycling of transferrin receptor to the plasma membrane (PubMed:22308388). {ECO:0000269|PubMed:11062261, ECO:0000269|PubMed:11788822, ECO:0000269|PubMed:15020713, ECO:0000269|PubMed:22308388}.
Subcellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane {ECO:0000269|PubMed:22308388}; Lipid-anchor. Note=Enriched in endosomes that are in close proximity to clathrin-enriched regions at the cell surface. {ECO:0000269|PubMed:22308388}.
Top Pathways Endocytosis

Rabenosyn-5 (C-19) - sc-82729 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Rabenosyn-5 (C-19): sc-82729. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic vesicles localization.

Rabenosyn-5 (H-138) - sc-367906 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Rabenosyn-5 (H-138): sc-367906. Western blot analysis of Rabenosyn-5 expression in COLO 205 (A), A-431 (B), HeLa (C), NCI-H1299 (D) and A549 (E) whole cell lysates.

Rabenosyn-5 (N-20) - sc-82730 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Rabenosyn-5 (S-17) - sc-82732 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Rabenosyn 5 antibody - ab190008 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Rabenosyn 5 antibody (ab190008) at 1/500 dilutionLane 1 : Jurkat cell lysateLane 2 : HUVEC cell lysateLane 3 : HUVEC cell lysate with synthesized peptide

Anti-Rabenosyn 5 antibody - ab138180 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Rabenosyn 5 antibody (ab138180) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-Rabenosyn 5 antibody - ab94356 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Rabenosyn 5 antibody (ab94356) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal stomach lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Rabenosyn 5 antibody - ab21196 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Rabenosyn 5 antibody - C-terminal - ab155247 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Rabenosyn 5 antibody - C-terminal (ab155247) at 1/1000 dilutionLane 1 : H1299 whole cell lysateLane 2 : Hela whole cell lysateLysates/proteins at 30 µg per lane.

Anti-RBSN / Rabenosyn 5 Antibody (aa129-178) - LS-C292217 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RBSN / Rabenosyn 5 Antibody (aa771-784) - LS-C55352 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of A431 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-RBSN / Rabenosyn 5 Antibody (N-Terminus) - LS-C110401 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ZFYVE20 / Rabenosyn 5 antibody LS-C110401 Western blot of Fetal Stomach lysate.

Anti-RBSN / Rabenosyn 5 Antibody (aa145-194) IHC-plus™ - LS-B9859 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ZFYVE20 / Rabenosyn 5 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9859 concentration 10 ug/ml.

Rabenosyn 5 Antibody - NBP1-92310 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Rabenosyn 5 Antibody [NBP1-92310] - Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.

Rabenosyn 5 Antibody - NB300-813 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Rabenosyn 5 Antibody - NBP1-33649 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Rabenosyn 5 Antibody [NBP1-33649] - Sample (30 ug of whole cell lysate) A: H1299 B: Hela 7. 5% SDS PAGE; antibody diluted at 1:1000.

Anti-ZFYVE20 antibody produced in rabbit - HPA044878 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZFYVE20: <B>Cat. No. HPA044878</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Anti-ZFYVE20, (N-terminal) antibody produced in rabbit - SAB2104434 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ZFYVE20, antibody produced in rabbit: <B>Cat. No. SAB2104434</B>: Immunoblotting analysis of ZFYVE20 in fetal stomach tissue lysate with ZFYVE20 anitbody at 1 μg/mL.

Anti-Rabenosyn 5 antibody produced in goat - SAB2500853 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Rabenosyn 5: <B>Cat. No. SAB2500853</B>: (0.3 μg/mL) staining of A431 lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-ZFYVE20 antibody produced in rabbit - SAB4502739 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ZFYVE20: <B>Cat. No. SAB4502739</B>: Immunoblotting analysis of extracts from HuvEc/Jurkat cells, using Anti-ZFYVE20 antibody. The lane on the left was treated with the Anti-ZFYVE20 antibody. The lane on the right (negative control) was treated with both Anti-ZFYVE20 antibody and the synthesized immunogen peptide.

RBNS5 Antibody - N-terminal region (ARP33265_P050) - ARP33265_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFYVE20 antibody - N-terminal region (ARP39547_P050) - ARP39547_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabenosyn-5-Antibody - AF1896a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1896a (0.3 µg/ml) staining of A431 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ZFYVE20 Antibody (OAAF04116) - OAAF04116 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ZFYVE20 Antibody (OAAF07301) - OAAF07301 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Search more