Gene Symbol | GOLPH3L |
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Entrez Gene | 55204 |
Alt Symbol | GPP34R |
Species | Human |
Gene Type | protein-coding |
Description | golgi phosphoprotein 3-like |
Other Description | GPP34-related protein|Golgi phosphoprotein 3-like |
Swissprots | B7Z6N3 Q9NVK0 Q9H4A5 B1AN09 |
Accessions | EAW53526 EAW53527 Q9H4A5 AJ296153 CAC13125 AK001549 BAA91750 AK300635 BAH13319 AK315594 BAG37966 BC013870 AAH13870 BI550986 BQ130668 BQ268076 DA513375 HQ447412 ADQ31898 XM_006711428 XP_006711491 XM_011509712 XP_011508014 XM_011509713 XP_011508015 XR_921864 NM_018178 NP_060648 |
Function | Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane. {ECO:0000269|PubMed:23345592}. |
Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:23345592}; Peripheral membrane protein {ECO:0000269|PubMed:23345592}; Cytoplasmic side {ECO:0000269|PubMed:23345592}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:23345592}; Peripheral membrane protein {ECO:0000269|PubMed:23345592}; Cytoplasmic side {ECO:0000269|PubMed:23345592}. Note=Phosphatidylinositol 4- phosphate (PtdIns4P)-binding mediates recruitment to Golgi membranes. |
Top Pathways | Transcriptional misregulation in cancer |
GOLPH3L CRISPR/Cas9 KO Plasmid (h) - sc-406637 from Santa Cruz Biotechnology
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GOLPH3L HDR Plasmid (h) - sc-406637-HDR from Santa Cruz Biotechnology
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GOLPH3L Double Nickase Plasmid (h) - sc-406637-NIC from Santa Cruz Biotechnology
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GOLPH3L Double Nickase Plasmid (h2) - sc-406637-NIC-2 from Santa Cruz Biotechnology
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GOLPH3L CRISPR Activation Plasmid (h) - sc-406637-ACT from Santa Cruz Biotechnology
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GOLPH3L CRISPR Activation Plasmid (h2) - sc-406637-ACT-2 from Santa Cruz Biotechnology
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GOLPH3L Lentiviral Activation Particles (h) - sc-406637-LAC from Santa Cruz Biotechnology
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GOLPH3L Lentiviral Activation Particles (h2) - sc-406637-LAC-2 from Santa Cruz Biotechnology
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GOLPH3L siRNA (h) - sc-88799 from Santa Cruz Biotechnology
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GOLPH3L shRNA Plasmid (h) - sc-88799-SH from Santa Cruz Biotechnology
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GOLPH3L shRNA (h) Lentiviral Particles - sc-88799-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU119281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9481 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10883 from Sigma-Aldrich
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GOLPH3L siRNA (Human) - CRJ0554 from Cohesion Biosciences
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GOLPH3L - MBS8237709 from MyBioSource
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shRNA set against Human GOLPH3L (NM_018178.5) - SHH305362 from Creative biogene
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Human GOLPH3L siRNA - orb271055 from Biorbyt
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GOLPH3L shRNA Plasmid (Human) - CHJ0554 from Cohesion Biosciences
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GOLPH3L miRNA 3'UTR clone - MiUTR4H-TG11347 from Creative biogene
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