| Gene Symbol |
GOLPH3L
|
| Entrez Gene |
55204
|
| Alt Symbol |
GPP34R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
golgi phosphoprotein 3-like
|
| Other Description |
GPP34-related protein|Golgi phosphoprotein 3-like
|
| Swissprots |
B7Z6N3 Q9NVK0 Q9H4A5 B1AN09
|
| Accessions |
EAW53526 EAW53527 Q9H4A5 AJ296153 CAC13125 AK001549 BAA91750 AK300635 BAH13319 AK315594 BAG37966 BC013870 AAH13870 BI550986 BQ130668 BQ268076 DA513375 HQ447412 ADQ31898 XM_006711428 XP_006711491 XM_011509712 XP_011508014 XM_011509713 XP_011508015 XR_921864 NM_018178 NP_060648
|
| Function |
Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane. {ECO:0000269|PubMed:23345592}.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:23345592}; Peripheral membrane protein {ECO:0000269|PubMed:23345592}; Cytoplasmic side {ECO:0000269|PubMed:23345592}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:23345592}; Peripheral membrane protein {ECO:0000269|PubMed:23345592}; Cytoplasmic side {ECO:0000269|PubMed:23345592}. Note=Phosphatidylinositol 4- phosphate (PtdIns4P)-binding mediates recruitment to Golgi membranes.
|
| Top Pathways |
Transcriptional misregulation in cancer
|
![Western Blot: GOLPH3L Overexpression Lysate (Adult Normal) [NBL1-11199] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GOLPH3L.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9201_GOLPH3L%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11199-img0002.jpg)