sev

Gene Symbol sev
Entrez Gene 32039
Alt Symbol 7LES, 7less, CG18085, CT3980, DROSEV, DROSEV1, DmHD-265, Dmel\CG18085, HD-265, SEV, Sev, sev(AC)[[14]]
Species Drosophila
Gene Type protein-coding
Description sevenless
Other Description CG18085-PA|sev-PA
Swissprots Q9VZ36 P13368 Q9U5V7 Q9TYI0
Accessions AAF47992 NM_078559 NP_511114
Function Receptor for an extracellular signal required to instruct a cell to differentiate into an R7 photoreceptor. The ligand for sev is the boss (bride of sevenless) protein on the surface of the neighboring R8 cell. {ECO:0000269|PubMed:2840202}.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Top Pathways MAPK signaling pathway - fly