| Gene Symbol | SEPT1 |
|---|---|
| Entrez Gene | 1731 |
| Alt Symbol | DIFF6, LARP, PNUTL3, SEP1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | septin 1 |
| Other Description | differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase)|peanut-like protein 3|septin-1|serologically defined breast cancer antigen NY-BR-24 |
| Swissprots | Q8WYJ6 Q8NEZ1 B4DVE6 Q9H285 Q658T1 Q96EL4 |
| Accessions | AAG48256 EAW52252 EAW52253 Q8WYJ6 AF085235 AAL40393 AK301045 BAG62658 AK303390 BAG64446 AL833004 CAH56484 AY034176 AAK61491 BC012161 AAH12161 BM663465 BQ072902 NM_052838 NP_443070 |
| Function | Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). {ECO:0000250, ECO:0000305}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis. |
| Tissue Specificity | Expressed at high levels in lymphoid and hematopoietic tissues. {ECO:0000269|PubMed:15915442}. |
| Top Pathways | Bacterial invasion of epithelial cells |