| Gene Symbol | TAF4 |
|---|---|
| Entrez Gene | 6874 |
| Alt Symbol | TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135 |
| Species | Human |
| Gene Type | protein-coding |
| Description | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa |
| Other Description | RNA polymerase II TBP-associated factor subunit C|TAF(II)130|TAF(II)135|TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135 kD|TAFII-130|TAFII-135|TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD|TBP-associated factor 4|transcription initiation factor TFIID 130 kDa subunit|transcription initiation factor TFIID 135 kD subunit|transcription initiation factor TFIID 135 kDa subunit|transcription initiation factor TFIID subunit 4 |
| Swissprots | Q99721 Q5TBP6 Q9BX42 Q9BR40 O00268 A6NGD9 |
| Accessions | AAT38111 EAW75406 EAW75407 O00268 AK097744 AK123937 BC167776 AAI67776 U75308 AAC50901 Y11354 CAA72189 NM_003185 NP_003176 |
| Function | Part of the TFIID complex, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Potentiates transcriptional activation by the AF-2S of the retinoic acid, vitamin D3 and thyroid hormone. |
| Subcellular Location | Nucleus. |
| Top Pathways | Huntington's disease, Herpes simplex infection, Basal transcription factors |