| Gene Symbol | CD34 |
|---|---|
| Entrez Gene | 947 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | CD34 molecule |
| Other Description | CD34 antigen|hematopoietic progenitor cell antigen CD34 |
| Swissprots | Q15971 Q5JTA3 Q9UJB1 Q15970 Q5JTA4 A8K664 P28906 |
| Accessions | AAA03659 BAE46748 CAJ01226 EAW93458 EAW93459 P28906 AA022917 AF202879 AAF14634 AF523361 AAM82157 AF538601 AAN15135 AK091890 AK291529 BAF84218 AK293030 BAF85719 AK294381 BAG57638 AK300835 BAG62486 BC039146 AAH39146 BX538076 CAD98000 BX640941 DQ891428 ABM82354 DQ894603 ABM85529 M81104 AAA03181 S53910 AAB25222 S53911 AAB25223 XM_011510170 XP_011508472 NM_001025109 NP_001020280 NM_001773 NP_001764 |
| Function | Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. |
| Top Pathways | Hematopoietic cell lineage, Cell adhesion molecules (CAMs) |