| Gene Symbol | ATP6V0D2 |
|---|---|
| Entrez Gene | 245972 |
| Alt Symbol | ATP6D2, VMA6 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 |
| Other Description | V-ATPase subunit d 2|V-type proton ATPase subunit d 2|vacuolar proton pump subunit d 2 |
| Swissprots | Q8N8Y2 |
| Accessions | EAW91631 EAW91632 Q8N8Y2 AK096027 BAC04679 AY079172 AAL87000 BC065207 AAH65207 XM_011516955 XP_011515257 NM_152565 NP_689778 |
| Function | Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). {ECO:0000250}. |
| Tissue Specificity | Kidney, osteoclast and lung. {ECO:0000269|PubMed:12384298}. |
| Top Pathways | Lysosome, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis, Synaptic vesicle cycle |