| Gene Symbol | ALG12 |
|---|---|
| Entrez Gene | 855764 |
| Alt Symbol | ECM39 |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase |
| Other Description | - |
| Swissprots | D6W1K4 P53730 |
| Accessions | DAA10570 P53730 NM_001183207 NP_014427 |
| Function | Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP- Man(7)GlcNAc(2)) required for protein glycosylation. {ECO:0000269|PubMed:10336995, ECO:0000269|PubMed:15987956}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}. |
| Top Pathways | N-Glycan biosynthesis, Various types of N-glycan biosynthesis |