TNNT2

Gene Symbol TNNT2
Entrez Gene 7139
Alt Symbol CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT
Species Human
Gene Type protein-coding
Description troponin T type 2 (cardiac)
Other Description cardiomyopathy, dilated 1D (autosomal dominant)|cardiomyopathy, hypertrophic 2|troponin T, cardiac muscle|troponin T2, cardiac
Swissprots Q99596 Q99597 Q9UM96 A8K3K6 O60214 A2TDB9 Q9BUF6 P45379
Accessions AAB30957 AAC39590 AAK92231 AAN71650 AAN71651 ABN05286 ABR09217 ABV48784 ABV48785 ABV48786 CAA70839 CAA70840 CAA70841 EAW91353 EAW91354 EAW91355 EAW91356 EAW91357 EAW91358 EAW91359 EAW91360 EAW91361 EAW91362 P45379 AA865519 AJ709280 AK055533 AK125236 AK290621 BAF83310 AK309493 AL832707 AY277394 AAP96757 BC002653 AAH02653 HQ447413 ADQ31899 L40162 AAA67422 S64668 AAB27731 S71125 AAD14076 S71126 AAB30956 X74819 CAA52818 X79855 CAA56235 X79856 CAA56236 X79858 CAA56238 X79859 CAA56239 X79861 CAA56240 X83743 X83744 XM_006711508 XP_006711571 XM_006711509 XP_006711572 XM_011509938 XP_011508240 XM_011509939 XP_011508241 XM_011509940 XP_011508242 XM_011509941 XP_011508243 XM_011509942 XP_011508244 XM_011509943 XP_011508245 XM_011509944 XP_011508246 XM_011509945 XP_011508247 XM_011509946 XP_011508248 NM_000364 NP_000355 NM_001001430 NP_001001430 NM_001001431 NP_001001431 NM_001001432 NP_001001432 NM_001276345 NP_001263274 NM_001276346 NP_001263275 NM_001276347 NP_001263276
Function Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Tissue Specificity Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
Top Pathways Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Dilated cardiomyopathy, Adrenergic signaling in cardiomyocytes

Troponin T (Cardiac) Antibody - 5593 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a human cardiac Troponin T (isoform 1) construct (+), using Troponin T (Cardiac) Antibody.

Troponin T-C (C-19) - sc-8121 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Troponin T-C (C-19): sc-8121. Western blot analysis of Troponin T-C expression in rat (A) and mouse (B) heart tissue extracts.

Troponin T-C (7e7) - sc-52289 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin T-C (7e7): sc-52289. Western blot analysis of Troponin T-C expression in human heart tissue extract.

Troponin T-C (2G3) - sc-33721 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin T-C (2G3): sc-33721. Western blot analysis of cardiac Troponin T expression in rat heart tissue extract.

Troponin T-C (1.BB.157) - sc-73237 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin T-C (1.BB.157): sc-73237. Western blot analysis of Troponin T-C expression in human heart tissue extract.

Troponin T-C (1F2) - sc-52284 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin T-C (1F2): sc-52284. Western blot analysis of Troponin T-C expression in human heart tissue extract.

Troponin T-C (1.BB.156) - sc-73238 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin T-C (1.BB.156): sc-73238. Western blot analysis of Troponin T-C expression in human heart tissue extract.

Troponin T-C (1.BB.155) - sc-73234 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Troponin T-C (1.BB.155): sc-73234. Western blot analysis of Troponin T-C expression in human heart tissue extract.

Anti-Cardiac Troponin T antibody - ab64623 from Abcam

Host Goat
Clonality Polyclonal
IHC image of Cardiac Troponin T  staining in human heart formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab64623, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Cardiac Troponin T antibody - ab115134 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cardiac Troponin T antibody (ab115134) at 1 µg/mlLane 1 : Heart (Mouse) Tissue LysateLane 2 : Heart (Rat) Tissue LysateLane 3 : Heart (Human) Whole Cell Lysate - fetal normal tissueLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Cardiac Troponin T antibody - ab80050 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Cardiac Troponin T antibody - ab129696 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cardiac Troponin T antibody (ab129696) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

Anti-Cardiac Troponin T antibody - ab89221 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Cardiac Troponin T antibody (ab89221) at 5 µg/ml + immunogen at 0.2 µgdeveloped using the ECL technique

Anti-cardiac Troponin T antibody - ab998 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-cardiac Troponin T antibody - ab999 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Cardiac Troponin T antibody [1C11] (Biotin) - ab105441 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 1C11

Anti-Cardiac Troponin T antibody [1C11] (FITC) - ab105439 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 1C11

Anti-Cardiac Troponin T antibody [1C11] (HRP) - ab105438 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 1C11

Anti-Cardiac Troponin T antibody [1C11] (Texas Red ®) - ab105440 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 1C11

Anti-Cardiac Troponin T antibody [1G1] - ab129364 from Abcam

Host Mouse
Clonality Monoclonal
Clone 1G1
ab129364 staining Cardiac Troponin T antigen by ELISA.

Anti-Cardiac Troponin T antibody [2f3] - ab38720 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 2f3

Anti-Cardiac Troponin T antibody [7e7] (HRP) - ab24452 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 7e7

Anti-Cardiac Troponin T antibody [7f4] - ab38717 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 7f4

Anti-Cardiac Troponin T antibody [7F4] (HRP) - ab10222 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 7F4

Anti-Cardiac Troponin T antibody [9g6] - ab38719 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 9g6
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