| Gene Symbol | ROT3 |
|---|---|
| Entrez Gene | 829790 |
| Alt Symbol | AP22.10, AP22_10, CYP90C1, ROTUNDIFOLIA 3 |
| Species | Arabidopsis thaliana |
| Gene Type | protein-coding |
| Description | 3-epi-6-deoxocathasterone 23-monooxygenase |
| Other Description | - |
| Swissprots | Q058J8 Q9M066 Q0WS16 O23242 |
| Accessions | AEE86649 CAW67788 CAW67806 CBC54106 CBC54144 CBD34584 Q9M066 BT029220 ABJ17155 NM_119801 NP_568002 |
| Function | C-23 hydroxylase involved in brassinosteroids biosynthesis. Converts directly (22S,24R)-22-hydroxy-5-alpha- ergostan-3-one and 3-epi-6-deoxocathasterone to 3-dehydro-6- deoxoteasterone and 6-deoxotyphasterol. These C-23 hydroxylation shortcuts bypass campestanol, 6-deoxocathasterone, and 6- deoxoteasterone. Functionally redundant with CYP90D1. {ECO:0000269|PubMed:15703058, ECO:0000269|PubMed:17138693}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15703058, ECO:0000269|PubMed:9694802}. |
| Top Pathways | Brassinosteroid biosynthesis |