| Gene Symbol | CD1B |
|---|---|
| Entrez Gene | 910 |
| Alt Symbol | CD1, CD1A, R1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | CD1b molecule |
| Other Description | CD1B antigen, b polypeptide|T-cell surface glycoprotein CD1b|cortical thymocyte antigen CD1B|differentiation antigen CD1-alpha-3 |
| Swissprots | Q5TDL0 Q9UMM2 P29016 Q5TDK9 |
| Accessions | AAA51936 AAA51940 AAD37579 EAW52841 P29016 AI336342 AK303329 BAG64394 AK303330 BAG64395 AK310617 BC069481 AAH69481 BC074747 AAH74747 BC104216 AAI04217 BC104217 AAI04218 CD687240 HQ448450 ADQ32930 M28826 AAA51939 XM_011510119 XP_011508421 NM_001764 NP_001755 |
| Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:10981968, ECO:0000269|PubMed:14716313}. |
| Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane. Lysosome membrane. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes. Localizes to cell surface lipid rafts. |
| Tissue Specificity | Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues. |
| Top Pathways | Hematopoietic cell lineage |