| Gene Symbol | Itp-r83A |
|---|---|
| Entrez Gene | 40664 |
| Alt Symbol | CG1063, DIP, DmInsP[[3R]], DmInsP[[3]]R, Dmel\CG1063, IP, IP3R, IP[[3]] receptor, IP[[3]]R, ITP-r83A, ITPR1, InsP[[3]], InsP[[3]]R, Insp3R, Ip3R, Itp-r, Itp-r-83A, Itp-r42B, Itp-r[1], anon-WO02059370.49, dIP[[3]]R, dip, itpr, itpr-83, l(3)05616, l(3)itpr, |
| Species | Drosophila |
| Gene Type | protein-coding |
| Description | Inositol 1,4,5,-tris-phosphate receptor |
| Other Description | 1, 4, 5-inositol trisphosphate receptor|CG1063-PA|CG1063-PB|CG1063-PC|IP3 receptor|IP[[3]] receptor|Inositol(1,4,5)-triphosphate receptor 42B|Ins(1,4,5)P[[3]] receptor|InsP[[3]] receptor|Itp-r83A-PA|Itp-r83A-PB|Itp-r83A-PC|dm_IP3 receptor|inositol 1,4,5,-tris-phosphate receptor|inositol 1,4,5-triphosphate receptor|inositol 1,4,5-trisphosphate (InsP3 ) receptor|inositol 1,4,5-trisphosphate receptor|inositol triphosphate receptor 1|inositol trisphosphate receptor|inositol-1,3,5,-trisphosphate receptor|inositol-1,4,5-trisphosphate receptor|type 1 InsP{3} receptor |
| Swissprots | Q9U981 Q24309 P29993 Q9VNC8 |
| Accessions | AAF52015 AAN13240 AHN57179 NM_001300251 NP_001287180 NM_169060 NP_730941 NM_169061 NP_730942 |
| Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. May be involved in visual and olfactory transduction, and myoblast proliferation. {ECO:0000269|PubMed:1322910}. |
| Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Tissue Specificity | Segmental expression of isoform B is first detected in stage 13 embryos in lateral and posterior epidermis. Expression extends to head region during stages 13-17: gnathal buds, clypeolabrum, procephalic lobe, labial organ and anterior sense organs. Adults exhibit high expression in antenna and lower expression in retina, head, legs and thorax. {ECO:0000269|PubMed:1322910, ECO:0000269|PubMed:1338312}. |
| Top Pathways | Phototransduction - fly, Phosphatidylinositol signaling system |