| Gene Symbol | CDS1 |
|---|---|
| Entrez Gene | 1040 |
| Alt Symbol | CDS |
| Species | Human |
| Gene Type | protein-coding |
| Description | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 |
| Other Description | CDP-DAG synthase 1|CDP-DG synthase 1|CDP-DG synthetase 1|CDP-diacylglycerol synthase 1|CDP-diglyceride pyrophosphorylase 1|CDP-diglyceride synthase 1|CDP-diglyceride synthetase 1|CDS 1|CTP:phosphatidate cytidylyltransferase 1|phosphatidate cytidylyltransferase 1 |
| Swissprots | B2RAL5 O00163 Q92903 |
| Accessions | EAX05950 EAX05951 Q92903 AI673547 AK026697 AK314245 BAG36912 AU139278 BC074833 AAH74833 BC074881 AAH74881 BE504303 CA313675 DN915398 U60808 AAC51184 U65887 AAC50735 XM_005262687 XP_005262744 NM_001263 NP_001254 |
| Function | Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Cytoplasmic aspect of the endoplasmic reticulum. {ECO:0000250}. |
| Tissue Specificity | Expressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate. Highly expressed in fetal kidney, lung and brain. Lower level in fetal liver. |
| Top Pathways | Glycerophospholipid metabolism, Phosphatidylinositol signaling system |