PVRL4

Gene Symbol PVRL4
Entrez Gene 81607
Alt Symbol EDSS1, LNIR, PRR4, nectin-4
Species Human
Gene Type protein-coding
Description poliovirus receptor-related 4
Other Description Ig superfamily receptor LNIR|nectin 4|nectin-4|poliovirus receptor-related protein 4
Swissprots B4DQW3 Q96K15 Q96NY8
Accessions CDM63684 CDM63771 CDM63773 CDM63774 CDM63775 CDM63777 CDM63778 EAW52665 EAW52666 Q96NY8 AB105191 BAQ19759 AB755430 BAM65001 AF160477 AAF82399 AF218028 AAG17270 AF426163 AAL23958 AK027753 BAB55344 AK298981 BAG61075 AK301481 BAG62996 BC010423 AAH10423 BC013892 BX641083 CF529301 DB223835 DQ893504 ABM84430 DQ896483 ABM87482 XM_005245508 XP_005245565 XM_011510021 XP_011508323 XM_011510022 XP_011508324 XM_011510023 XP_011508325 NM_030916 NP_112178
Function Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells.
Subcellular Location Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell junction, adherens junction {ECO:0000269|PubMed:11544254}. Note=Colocalizes with MLLT4 at cadherin-based adherens junctions.
Tissue Specificity Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. {ECO:0000269|PubMed:11544254, ECO:0000269|PubMed:17474988}.
Top Pathways Adherens junction

Nectin 4 CRISPR/Cas9 KO Plasmid (h) - sc-410167 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nectin 4 HDR Plasmid (h) - sc-410167-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nectin 4 Double Nickase Plasmid (h) - sc-410167-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nectin 4 Double Nickase Plasmid (h2) - sc-410167-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nectin 4 CRISPR Activation Plasmid (h) - sc-410167-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nectin 4 CRISPR Activation Plasmid (h2) - sc-410167-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nectin 4 Lentiviral Activation Particles (h) - sc-410167-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nectin 4 Lentiviral Activation Particles (h2) - sc-410167-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nectin 4 siRNA (h) - sc-62669 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nectin 4 shRNA Plasmid (h) - sc-62669-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nectin 4 shRNA (h) Lentiviral Particles - sc-62669-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nectin-4/PVRL4 RNAi - H00081607-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU118921 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN17752 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17752 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07666 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07666

PVRL4 siRNA (Human) - CRJ3017 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PVRL4 (NM_030916.2) - SHH387216 from Creative biogene

Category siRNA
Species Reactivities Human

PVRL4 shRNA Plasmid (Human) - CHJ3017 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PVRL4 miRNA 3'UTR clone - MiUTR1H-08507 from Creative biogene

Species Reactivities Human
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