Gene Symbol | ADM2 |
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Entrez Gene | 79924 |
Alt Symbol | AM2, dJ579N16.4 |
Species | Human |
Gene Type | protein-coding |
Description | adrenomedullin 2 |
Other Description | intermedin |
Swissprots | Q3LFQ0 Q7Z4H4 |
Accessions | EAW73541 Q7Z4H4 AB121034 BAD07411 AB236970 BAE46395 AF529213 AAQ09100 AK024788 BAB15004 AK090635 AK092640 AK225097 BC012864 BC141534 AAI41535 BC146569 AAI46570 BM910446 BX400262 CR456479 CAG30365 CU013029 CAK54460 CU013317 CAK54759 NM_001253845 NP_001240774 NM_024866 NP_079142 |
Function | IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway. {ECO:0000269|PubMed:14615490}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary. {ECO:0000269|PubMed:14615490, ECO:0000269|PubMed:16359754}. |
ADM2 CRISPR/Cas9 KO Plasmid (h) - sc-403726 from Santa Cruz Biotechnology
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ADM2 HDR Plasmid (h) - sc-403726-HDR from Santa Cruz Biotechnology
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ADM2 Double Nickase Plasmid (h) - sc-403726-NIC from Santa Cruz Biotechnology
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ADM2 Double Nickase Plasmid (h2) - sc-403726-NIC-2 from Santa Cruz Biotechnology
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ADM2 CRISPR Activation Plasmid (h) - sc-403726-ACT from Santa Cruz Biotechnology
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ADM2 CRISPR Activation Plasmid (h2) - sc-403726-ACT-2 from Santa Cruz Biotechnology
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ADM2 Lentiviral Activation Particles (h) - sc-403726-LAC from Santa Cruz Biotechnology
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ADM2 Lentiviral Activation Particles (h2) - sc-403726-LAC-2 from Santa Cruz Biotechnology
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ADM2 siRNA (h) - sc-72452 from Santa Cruz Biotechnology
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ADM2 shRNA Plasmid (h) - sc-72452-SH from Santa Cruz Biotechnology
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ADM2 shRNA (h) Lentiviral Particles - sc-72452-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU076341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2887 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2887 from Sigma-Aldrich
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ADM2 siRNA (Human) - CRJ2669 from Cohesion Biosciences
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ADM2 - MBS8231321 from MyBioSource
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shRNA set against Human Adm2 (NM_024866.5) - SHH232514 from Creative biogene
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Human ADM2 siRNA - orb273170 from Biorbyt
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ADM2 shRNA Plasmid (Human) - CHJ2669 from Cohesion Biosciences
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ADM2 miRNA 3'UTR clone - MiUTR4H-TG00179 from Creative biogene
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