CDC16

Gene Symbol	CDC16
Entrez Gene	8881
Alt Symbol	ANAPC6, APC6, CUT9
Species	Human
Gene Type	protein-coding
Description	cell division cycle 16
Other Description	CDC16Hs|anaphase-promoting complex subunit 6|anaphase-promoting complex, subunit 6|cell division cycle 16 homolog|cell division cycle protein 16 homolog|cyclosome subunit 6
Swissprots	Q9Y564 Q13042 Q96AE6 Q7Z651 Q5T8C8 A2A365
Accessions	AAS94323 CCQ43240 EAX09237 EAX09238 EAX09239 EAX09240 EAX09241 EAX09242 EAX09243 EAX09244 EAX09245 Q13042 AB209850 BAD93087 AF164598 AAD45156 AK095082 AK296424 BAG59086 AK315302 BAG37707 AL540490 BC010875 AAH10875 BC017244 AAH17244 BC050575 U18291 AAC50200 XM_005266204 XP_005266261 XM_005266206 XP_005266263 XM_006719992 XP_006720055 XM_006719993 XP_006720056 XM_011534851 XP_011533153 XM_011534852 XP_011533154 XM_011534853 XP_011533155 XR_245358 XR_245359 XR_245360 XR_941424 NM_001078645 NP_001072113 NM_003903 NP_003894
Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:7736578}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:7736578}. Note=Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle.
Top Pathways	Cell cycle, Ubiquitin mediated proteolysis, Progesterone-mediated oocyte maturation, Oocyte meiosis, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Apc6 full length protein - ab160243 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Apc6 protein fragment - ab160244 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

APC6 / CDC16 Antibody Blocking Peptide - LS-E30915 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

APC6 / CDC16 Antibody Blocking Peptide - LS-E21674 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CDC16 Protein - H00008881-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CDC16 Partial Recombinant Protein - H00008881-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

CDC16 Blocking Peptide - NBP1-77155PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

CDC16 Blocking Peptide - abx161333 from Abbexa Category Peptide Species Human, Monkey, Pig

CDC16 / APC6 - H00008881-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDC16 / APC6 - H00008881-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CDC16 / APC6 - H00008881-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDC16 / APC6 - H00008881-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CDC16 / APC6 Control Peptide - AP30062CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

APC6 Peptide - 5729P from ProSci Category Peptide Species Human

CDC16 fusion protein - ag5801 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CDC16 fusion protein - Ag5427 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CDC16 Blocking Peptide - CBP3832 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey, Pig

Cdc16 (K556) Peptide - BS1621P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Cdc16 (E206) Peptide - BS2202P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Cell division cycle protein 16 homolog(CDC16) - CSB-YP618753HU CSB-EP618753HU CSB-BP618753HU CSB-MP618753HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CDC16 / APC6 (transcript variant 1) - TP305639 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CDC16 / APC6 (transcript variant 2) - TP324869 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Cell division cycle protein 16 homolog (CDC16), Recombinant Protein - MBS1482834 from MyBioSource Category Protein Prices $1,415.00, $1,415.00, $1,645.00, $1,645.00, $2,390.00, $2,390.00, $2,835.00, $2,835.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CDC16 Recombinant Protein Antigen - NBP1-89094PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CDC16-Antibody-N-term-Blocking-Peptide - BP9572a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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