Gene Symbol |
MPI
|
Entrez Gene |
4351
|
Alt Symbol |
CDG1B, PMI, PMI1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
mannose phosphate isomerase
|
Other Description |
mannose-6-phosphate isomerase|phosphohexomutase|phosphomannose isomerase 1
|
Swissprots |
A8K8K9 Q96AB0 P34949
|
Accessions |
AAF37697 EAW99295 EAW99296 EAW99297 EAW99298 P34949 AF504648 AAM28199 AK096520 AK225149 AK292374 BAF85063 AK294030 BAG57385 AK301370 BAG62912 AK302354 BAG63680 AW445009 AW813817 BC017351 AAH17351 BC046357 AAH46357 BX648475 CD706167 HQ448582 ADQ33060 X76057 CAA53657 XM_011521592 XP_011519894 XM_011521593 XP_011519895 NM_001289155 NP_001276084 NM_001289156 NP_001276085 NM_001289157 NP_001276086 NM_002435 NP_002426
|
Function |
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
|
Subcellular Location |
Cytoplasm {ECO:0000305}.
|
Tissue Specificity |
Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
|
Top Pathways |
Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism
|