| Gene Symbol | CA12 |
|---|---|
| Entrez Gene | 771 |
| Alt Symbol | CAXII, HsT18816 |
| Species | Human |
| Gene Type | protein-coding |
| Description | carbonic anhydrase XII |
| Other Description | CA-XII|carbonate dehydratase XII|carbonic anhydrase 12|carbonic dehydratase|tumor antigen HOM-RCC-3.1.3 |
| Swissprots | Q9BWG2 B2RE24 O43570 Q53YE5 |
| Accessions | EAW77646 EAW77647 EAW77648 EAW77649 EAW77650 O43570 AF037335 AAC63952 AF051882 AAC39789 AK000158 BAA90981 AK096845 BAG53376 AK315769 BAG38121 BC000278 AAH00278 BC001012 AAH01012 BC011691 AAH11691 BC023981 AAH23981 BC087838 BM994285 BQ440047 BT006656 AAP35302 BU167720 BU944741 CA309380 DA509400 DA546357 DQ893188 ABM84114 DQ896511 ABM87510 EU831616 ACE87216 EU831623 ACE87223 EU831703 ACE86537 EU831708 ACE86542 NM_001218 NP_001209 NM_001293642 NP_001280571 NM_206925 NP_996808 |
| Function | Reversible hydration of carbon dioxide. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. |
| Top Pathways | Nitrogen metabolism |