Gene Symbol |
UBE2D4
|
Entrez Gene |
51619
|
Alt Symbol |
HBUCE1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ubiquitin-conjugating enzyme E2D 4 (putative)
|
Other Description |
ubiquitin carrier protein D4|ubiquitin-conjugating enzyme E2 D4|ubiquitin-conjugating enzyme HBUCE1|ubiquitin-protein ligase D4
|
Swissprots |
Q9Y2X8 A4D1V0
|
Accessions |
EAL24010 EAW94178 EAW94179 EAW94180 EAW94181 EAW94182 EAW94183 EAW94184 Q9Y2X8 AF125044 AAD31180 AF125045 AAD31181 AK001446 BAA91697 AK056566 AW014299 BC004104 AAH04104 BG499454 HQ447284 ADQ31771 XM_006715734 XP_006715797 XM_006715735 XP_006715798 XM_006715736 XP_006715799 XM_011515420 XP_011513722 XM_011515421 XP_011513723 XM_011515422 XP_011513724 XM_011515423 XP_011513725 NM_015983 NP_057067
|
Function |
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked polyubiquitination. {ECO:0000269|PubMed:20061386}.
|
Top Pathways |
Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum
|