CDIPT

Gene Symbol CDIPT
Entrez Gene 10423
Alt Symbol PIS, PIS1
Species Human
Gene Type protein-coding
Description CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Other Description PI synthase|PtdIns synthase|phosphatidylinositol synthase
Swissprots Q6FGU1 B4DUV0 O14735 H3BTV1 Q6ZN70
Accessions EAW79976 EAW79977 EAW79978 O14735 AF014807 AAB94860 AI696848 AK094468 BAG52872 AK097691 BAG53514 AK131227 BAG54756 AK131349 BAD18505 AK222676 BAD96396 AK290632 BAF83321 AK300805 BAG62462 AK310988 AK314544 AL050383 BC001444 AAH01444 BI490060 BT007301 AAP35965 BX333193 CR542016 CAG46813 XM_005255038 XP_005255095 NM_001286585 NP_001273514 NM_001286586 NP_001273515 NM_006319 NP_006310 NM_145752
Function Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme. {ECO:0000269|PubMed:8110188}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane {ECO:0000269|PubMed:8110188}.
Tissue Specificity Detected in placenta (at protein level). Widely expressed. Higher expression in adult liver and skeletal muscle, slightly lower levels seen in pancreas, kidney, lung, placenta, brain, heart, leukocyte, colon, small intestine, ovary, testis, prostate, thymus and spleen. In fetus, expressed in kidney, liver, lung and brain. {ECO:0000269|PubMed:8110188}.
Top Pathways Inositol phosphate metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system

PIS1 (C-2) - sc-514255 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PIS1 (C-2): sc-514255. Western blot analysis of PIS1 expression in HeLa whole cell lysate (A) and human stomach tissue extract (B).

PIS1 (Q-18) - sc-139417 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
PIS1 (Q-18): sc-139417. Western blot analysis of PIS1 expression in non-transfected: sc-117752 (A) and mouse PIS1 transfected: sc-127338 (B) 293T whole cell lysates.

Anti-CDIPT1 antibody - ab94958 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CDIPT1 antibody (ab94958) at 1/100 dilution + mouse stomach tissue lysate at 35 µg

Anti-CDIPT Antibody (Internal, AP) - LS-C254376 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDIPT Antibody (Internal, APC) - LS-C254378 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDIPT Antibody (Internal, PE) - LS-C254383 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDIPT Antibody (Internal, Biotin) - LS-C254381 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDIPT Antibody (Internal, Azide-free, HRP) - LS-C254382 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDIPT Antibody (Internal) - LS-C320253 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CDIPT Antibody - LS-C306877 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal

Anti-CDIPT Antibody - LS-C168611 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue reacted with CDIPT Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CDIPT Antibody (Internal, FITC) - LS-C254380 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

CDIPT Antibody - NBP1-91775 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CDIPT Antibody [NBP1-91775] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY416733)

CDIPT Antibody (1F8) - H00010423-M02A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1F8

Monoclonal Anti-CDIPT antibody produced in mouse - SAB1403066 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1F8

Anti-CDIPT antibody produced in rabbit - HPA045185 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CDIPT: <B>Cat. No. HPA045185</B>: Immunohistochemical staining of human adrenal gland shows strong cytoplasmic and nuclear positivity in glandular cells.

ANTI-CDIPT (CENTER) antibody produced in rabbit - SAB1303074 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>CDIPT (Center): <B>Cat. No. SAB1303074</B>: CDIPT in Human brain tissue with CDIPT antibody (Center) at 5 μg/mL.

CDIPT-Antibody-Center - AP9044c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of CDIPT Antibody (Center) (Cat. #AP9044c) in mouse stomach tissue lysates (35ug/lane). CDIPT (arrow) was detected using the purified Pab.

CDIPT Antibody - middle region (OAAB05631) - OAAB05631 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CDIPT antibody, Internal - GTX80599 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-CDIPT antibody, Internal used in Flow cytometry/FACS. GTX80599
Search more