| Gene Symbol | C1S |
|---|---|
| Entrez Gene | 716 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | complement component 1, s subcomponent |
| Other Description | C1 esterase|basic proline-rich peptide IB-1|complement C1s subcomponent|complement component 1 subcomponent s |
| Swissprots | Q9UCU8 Q9UCU7 Q9UM14 Q9UCV2 Q9UCU9 Q9UCV5 D3DUT4 Q9UCV0 Q9UCV3 Q9UCV1 P09871 Q9UCV4 |
| Accessions | BAA86864 CBJ05772 CBJ21224 EAW88689 EAW88690 P09871 AK025309 AK126711 AK290295 BAF82984 AM886411 AU100335 BC056903 AAH56903 CD358820 DB257339 DB265957 J04080 AAA51852 M18767 AAA51853 XM_005253760 XP_005253817 NM_001734 NP_001725 NM_201442 NP_958850 |
| Function | C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. |
| Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Staphylococcus aureus infection, Pertussis |