TDP-43/TARDBP Antibody

Name	TDP-43/TARDBP Antibody
Supplier	Novus Biologicals
Catalog	NB110-55376
Prices	$309.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal
Applications	WB ICC/IF IHC
Species Reactivities	Human, Mouse, Chicken, Primate, Xenopus, Zebrafish
Antigen	A synthetic peptide to a C-terminal region [within residues 350-414] of the human TARDBP protein. [Swiss-Prot# Q13148]
Purity/Format	Immunogen affinity purified
Blocking Peptide	TDP-43/TARDBP Blocking Peptide
Description	Rabbit Polyclonal
Gene	TARDBP
Supplier Page	Shop

Product images

Western Blot: TARDBP Antibody [NB110-55376] - Cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY TARDBP cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TARDBP.

Immunocytochemistry/Immunofluorescence: TARDBP Antibody [NB110-55376] - TARDBP antibody was tested in MCF-7 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Western Blot: TARDBP Antibody [NB110-55376] - TARDBP antibody was tested in HeLa WCE.

Product References

Downregulation of VAPB expression in motor neurons derived from induced - Downregulation of VAPB expression in motor neurons derived from induced

Mitne-Neto M, Machado-Costa M, Marchetto MC, Bengtson MH, Joazeiro CA, Tsuda H, Bellen HJ, Silva HC, Oliveira AS, Lazar M, Muotri AR, Zatz M. Hum Mol Genet. 2011 Sep 15;20(18):3642-52.

TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer - TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer

Kawahara Y, Mieda-Sato A. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3347-52. doi:

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar - TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar

Wegorzewska I, Bell S, Cairns NJ, Miller TM, Baloh RH. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18809-14. doi:

Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in - Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in

Geser F, Brandmeir NJ, Kwong LK, Martinez-Lage M, Elman L, McCluskey L, Xie SX, Lee VM, Trojanowski JQ. Arch Neurol. 2008 May;65(5):636-41.

Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular - Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular

Schmid B, Hruscha A, Hogl S, Banzhaf-Strathmann J, Strecker K, van der Zee J, Teucke M, Eimer S, Hegermann J, Kittelmann M, Kremmer E, Cruts M, Solchenberger B, Hasenkamp L, van Bebber F, Van Broeckhoven C, Edbauer D, Lichtenthaler SF, Haass C. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):4986-91. doi:

TDP-43 dimerizes in human cells in culture. - TDP-43 dimerizes in human cells in culture.

Shiina Y, Arima K, Tabunoki H, Satoh J. Cell Mol Neurobiol. 2010 May;30(4):641-52.

Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by - Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by

Udan-Johns M, Bengoechea R, Bell S, Shao J, Diamond MI, True HL, Weihl CC, Baloh RH. Hum Mol Genet. 2014 Jan 1;23(1):157-70.

Full-length TDP-43 forms toxic amyloid oligomers that are present in - Full-length TDP-43 forms toxic amyloid oligomers that are present in

Fang YS, Tsai KJ, Chang YJ, Kao P, Woods R, Kuo PH, Wu CC, Liao JY, Chou SC, Lin V, Jin LW, Yuan HS, Cheng IH, Tu PH, Chen YR. Nat Commun. 2014 Sep 12;5:4824.

The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity. - The cleavage pattern of TDP-43 determines its rate of clearance and cytotoxicity.

Li Q, Yokoshi M, Okada H, Kawahara Y. Nat Commun. 2015 Jan 29;6:6183.

TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a - TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a

Goossens J, Vanmechelen E, Trojanowski JQ, Lee VM, Van Broeckhoven C, van der Zee J, Engelborghs S. Acta Neuropathol Commun. 2015 Apr 1;3:15.