| Name | PARP-14 Antibody |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 251941 |
| Prices | $292.00 |
| Sizes | 100 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Applications | ELISA WB |
| Species Reactivities | Human |
| Antigen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PARP-14. |
| Purity/Format | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| Description | Poly [ADP-ribose] polymerase 14 (PARP-14) functions as a transcriptional switch for Stat6-dependent gene induction. In the absence of a signal, PARP-14 acts as a transcriptional repressor by recruiting histone deacetylases (HDACs). In contrast, in the presence of IL-4 the catalytic activity of PARP-14 facilitates Stat6 binding to the promoter, and release of HDACs so as to activate transcription. |
| Gene | PARP14 |
| Supplier Page | Shop |