Anti-EED antibody
| Name | Anti-EED antibody |
|---|---|
| Supplier | Abcam |
| Catalog | ab4469 |
| Prices | $391.00 |
| Sizes | 100 µg |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | WB IP ICC/IF ICC/IF IHC-F |
| Species Reactivities | Bovine, Human, Mouse, Chicken, Xenopus |
| Antigen | Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human EED |
| Description | Rabbit Polyclonal |
| Gene | EED |
| Conjugate | Unconjugated |
| Supplier Page | Shop |
Product images
Rabbit polyclonal to EED (ab4469) on U20S cells. Antibody used at 1/100.U20S cells were fixed with PFA (3.7%), permeabilised with PBS 0.1% Triton. Counterstained with Hoechst. Cells were examined with Axioplan 2 microscope (Zeiss).Secondary antibody: donkey anti-rabbit (Cy3).
Anti-EED antibody (ab4469) at 1/250 dilution + EED Recombinant Protein (Human) at 0.1 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.
Product References
EZH2 expands breast stem cells through activation of NOTCH1 signaling. - EZH2 expands breast stem cells through activation of NOTCH1 signaling.
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PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral - PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral
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EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and - EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and
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Identification and Validation of a Putative Polycomb Responsive Element in the - Identification and Validation of a Putative Polycomb Responsive Element in the
Bengani H, Mendiratta S, Maini J, Vasanthi D, Sultana H, Ghasemi M, Ahluwalia J, Ramachandran S, Mishra RK, Brahmachari V. PLoS One. 2013 Jun 21;8(6):e67217. Print 2013.
Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. - Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.
Kim W, Bird GH, Neff T, Guo G, Kerenyi MA, Walensky LD, Orkin SH. Nat Chem Biol. 2013 Oct;9(10):643-50.
EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, - EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU,
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Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively - Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively
Yap DB, Chu J, Berg T, Schapira M, Cheng SW, Moradian A, Morin RD, Mungall AJ, Meissner B, Boyle M, Marquez VE, Marra MA, Gascoyne RD, Humphries RK, Arrowsmith CH, Morin GB, Aparicio SA. Blood. 2011 Feb 24;117(8):2451-9.
Enhancer of zeste homolog 2 overexpression has a role in the development of - Enhancer of zeste homolog 2 overexpression has a role in the development of
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(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a - (-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a
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The Polycomb group protein EED couples TNF receptor 1 to neutral - The Polycomb group protein EED couples TNF receptor 1 to neutral
Philipp S, Puchert M, Adam-Klages S, Tchikov V, Winoto-Morbach S, Mathieu S, Deerberg A, Kolker L, Marchesini N, Kabelitz D, Hannun YA, Schutze S, Adam D. Proc Natl Acad Sci U S A. 2010 Jan 19;107(3):1112-7. doi: